Berberine Elite

Evidence-based formulation rationale and clinical references

Berberine Elite is formulated using high-purity, patented berberine supported by multiple RCTs and meta-analyses demonstrating benefits across glucose control, lipid regulation, insulin resistance, and inflammatory modulation.

Key Scientific Takeaways

• AMPK Activation (Metabolic Master Switch)
  Berberine activates AMP-activated protein kinase (AMPK), improving insulin signalling, glucose uptake (GLUT-4), and energy homeostasis.

• Insulin Resistance & PCOS Support
  Clinical evidence shows berberine improves insulin resistance and ovulation outcomes in PCOS, matching metformin in several studies.

• Lipid Profile Improvement
  Reduces total cholesterol, LDL-C, and triglycerides in metabolic syndrome.

• Anti-inflammatory & Antioxidant Effects
  Lowers inflammatory and oxidative stress markers associated with metabolic disorders.

• Gut Microbiome Interaction
  Berberine’s gut-level activity modulates microbiota, contributing to systemic metabolic benefits.

• Generally well tolerated

• Occasional GI upset (constipation or diarrhoea)

• Avoid during pregnancy & breastfeeding

• Use with caution in severe hepatic or renal impairment

• May interact with medications metabolised via CYP3A4 / P-glycoprotein (e.g., blood thinners)

1. Is berberine similar to metformin?
Berberine activates AMPK pathways similar to metformin and has shown comparable effects on insulin resistance in clinical studies.

2. Why does purity matter in berberine supplements?
Lower-grade extracts vary widely in potency. Patented Rebersa® ensures 98% purity and batch-to-batch consistency.

3. Can this be used for PCOS?
Yes. Clinical evidence supports berberine for insulin resistance and ovulatory support in PCOS under professional guidance.

4. Is Berberine Elite safe for long-term use?
When used at clinical doses and under guidance, berberine is generally safe for long-term metabolic support.